Fibroblast Activation Protein Inhibitor FAPI
A Promising Duet on the Theranostics Stage
Fibroblast activation protein inhibitors (FAPIs) are a novel group of molecules that target the Fibroblast activation protein (FAP), which is overexpressed in cancer-associated fibroblasts (CAFs).
FAPIs are of special interest since they are promising theranostic molecules that can target various malignant tumors.
Recent findings have demonstrated that FAPIs may compete with 18FDG in terms of pan-tumors indications without the shortcomings of FDG and with attractive theranostic properties.
The image below gained “The Image of The Year” title at the 66th SNMMI Annual Meeting, June 22-25, 2019, Anaheim, CA. USA.